Neurological Autosomal Dominant

Huntington Disease

A progressive brain disorder causing uncontrolled movements, emotional problems, and loss of thinking ability. Symptoms typically begin in adulthood.

Genetic Information

Associated Gene

HTT

Inheritance Pattern

Autosomal Dominant

Carrier Frequency

1 in 10,000

Signs and Symptoms
  • Involuntary movements (chorea)
  • Difficulty walking and speaking
  • Memory and concentration problems
  • Depression and mood changes
Treatment and Management
Currently, only supportive care is available for this condition.

Symptom management only; no cure or disease-modifying treatment

How Is It Inherited?

This condition follows an autosomal dominant inheritance pattern. This means:

  • Only one copy of the altered gene is needed to cause the condition
  • An affected person has a 50% chance of passing it to each child
  • The condition can appear in every generation of an affected family
Medical Reference

For detailed clinical information, visit the GeneReviews article:

GeneReviews: Huntington Disease
Quick Facts
Category Neurological
Inheritance Autosomal Dominant
Gene(s) HTT
Treatable No
Have Questions?

Speak with a board-certified genetic counselor to learn more about this condition and what it means for you.

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Disclaimer: This information is for educational purposes only and should not replace professional genetic counseling. If you have questions about genetic test results, please consult with a certified genetic counselor.